Item Type | Name |
Concept
|
Acetates
|
Concept
|
Actins
|
Concept
|
Adenocarcinoma
|
Concept
|
Aminocaproates
|
Concept
|
Age Factors
|
Concept
|
Antibiotics, Antineoplastic
|
Concept
|
Antibodies, Neoplasm
|
Concept
|
Air Pollutants
|
Concept
|
alpha-Fetoproteins
|
Concept
|
Acrylamides
|
Concept
|
Abscess
|
Concept
|
Acetylcysteine
|
Concept
|
Algorithms
|
Concept
|
Analgesics, Opioid
|
Concept
|
Alleles
|
Concept
|
Amino Acid Sequence
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Administration, Oral
|
Concept
|
Body Fluids
|
Concept
|
Breast
|
Concept
|
Antineoplastic Agents
|
Concept
|
Carcinoma, Squamous Cell
|
Concept
|
Cell Line, Transformed
|
Concept
|
Carcinoid Tumor
|
Concept
|
Carcinoma
|
Concept
|
Carcinoma, Bronchogenic
|
Concept
|
Chromosomes, Human, Pair 11
|
Concept
|
Chromosomes, Human, Pair 6
|
Concept
|
Antioxidants
|
Concept
|
Anesthetics
|
Concept
|
Antibodies, Monoclonal
|
Concept
|
Cytogenetics
|
Concept
|
B-Lymphocytes
|
Concept
|
Base Sequence
|
Concept
|
Benzamides
|
Concept
|
Cell Count
|
Concept
|
Cell Nucleus
|
Concept
|
Bacterial Infections
|
Concept
|
Bayes Theorem
|
Concept
|
Benzopyrans
|
Concept
|
DNA Damage
|
Concept
|
Blood Vessels
|
Concept
|
China
|
Concept
|
Carcinoma, Renal Cell
|
Concept
|
Bilirubin
|
Concept
|
Bile Duct Neoplasms
|
Concept
|
Biological Products
|
Concept
|
Biopsy
|
Concept
|
Blastomycosis
|
Concept
|
California
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
Concept
|
Cattle
|
Concept
|
Cell Membrane
|
Concept
|
Cell Division
|
Concept
|
Boronic Acids
|
Concept
|
Ethanolamines
|
Concept
|
Chromosomes, Human, Pair 21
|
Concept
|
Cell Adhesion
|
Concept
|
Chromosomes, Human, Pair 12
|
Concept
|
Chicago
|
Concept
|
Cisplatin
|
Concept
|
Glutathione Transferase
|
Concept
|
Cholesterol
|
Concept
|
Clathrin
|
Concept
|
Contrast Media
|
Concept
|
Diabetes Mellitus, Type 1
|
Concept
|
Dacarbazine
|
Concept
|
Cytoplasm
|
Concept
|
Deoxyglucose
|
Concept
|
Emigration and Immigration
|
Concept
|
Endothelium, Vascular
|
Concept
|
Cytoskeleton
|
Concept
|
DNA Repair
|
Concept
|
Echocardiography
|
Concept
|
Cyclophosphamide
|
Concept
|
Electrophysiology
|
Concept
|
Estradiol
|
Concept
|
Leukemia, Megakaryoblastic, Acute
|
Concept
|
Chromones
|
Concept
|
Chromosomes, Human, Pair 9
|
Concept
|
Exons
|
Concept
|
Mass Screening
|
Concept
|
Erythropoietin
|
Concept
|
Etoposide
|
Concept
|
Drug Evaluation, Preclinical
|
Concept
|
Introns
|
Concept
|
Microtubule-Associated Proteins
|
Concept
|
Myasthenia Gravis
|
Concept
|
Genes
|
Concept
|
Fatty Acids
|
Concept
|
Fibroblast Growth Factors
|
Concept
|
Jejunal Neoplasms
|
Concept
|
Oncogenes
|
Concept
|
Electromyography
|
Concept
|
Hydrogen Peroxide
|
Concept
|
Liver Neoplasms
|
Concept
|
Insulin-Like Growth Factor I
|
Concept
|
Energy Metabolism
|
Concept
|
Epithelium
|
Concept
|
Herpesvirus 4, Human
|
Concept
|
Fibrinopeptide A
|
Concept
|
Flow Cytometry
|
Concept
|
Fluorescent Antibody Technique
|
Concept
|
Multigene Family
|
Concept
|
Leukocytes, Mononuclear
|
Concept
|
Keratins
|
Concept
|
Carcinoma, Hepatocellular
|
Concept
|
Leukocytes
|
Concept
|
Microfilament Proteins
|
Concept
|
Extracellular Matrix
|
Concept
|
Primary Health Care
|
Concept
|
Immunohistochemistry
|
Concept
|
Molecular Sequence Data
|
Concept
|
NADP
|
Concept
|
Glycolysis
|
Concept
|
Pubic Bone
|
Concept
|
Oxidative Phosphorylation
|
Concept
|
Pancreatic Neoplasms
|
Concept
|
Molecular Biology
|
Concept
|
Cricetinae
|
Concept
|
Interleukin-3
|
Concept
|
Genes, Intracisternal A-Particle
|
Concept
|
Lymphokines
|
Concept
|
Fetal Blood
|
Concept
|
Prostatic Neoplasms
|
Concept
|
Image Processing, Computer-Assisted
|
Concept
|
Rats, Inbred F344
|
Concept
|
Recurrence
|
Concept
|
Receptors, Cell Surface
|
Concept
|
Repressor Proteins
|
Concept
|
Residence Characteristics
|
Concept
|
Risk Factors
|
Concept
|
Prothrombin Time
|
Concept
|
Semen
|
Concept
|
Radiation Dosage
|
Concept
|
Receptors, Antigen, B-Cell
|
Concept
|
Receptors, Immunologic
|
Concept
|
Intermediate Filament Proteins
|
Concept
|
Rotenone
|
Concept
|
Cohort Studies
|
Concept
|
Genes, ras
|
Concept
|
Cadherins
|
Concept
|
Sulfites
|
Concept
|
Leukocyte Count
|
Concept
|
Incidence
|
Concept
|
Cluster Analysis
|
Concept
|
Endothelial Growth Factors
|
Concept
|
Transcription, Genetic
|
Concept
|
Protein Biosynthesis
|
Concept
|
Tissue Banks
|
Concept
|
Superoxides
|
Concept
|
Software
|
Concept
|
Genes, abl
|
Concept
|
CHO Cells
|
Concept
|
Electric Impedance
|
Concept
|
Caenorhabditis elegans
|
Concept
|
Hepatocyte Growth Factor
|
Concept
|
Clinical Trials, Phase I as Topic
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Receptors, Opioid, mu
|
Concept
|
Thiocarbamates
|
Concept
|
Drug Design
|
Concept
|
Vaccination
|
Concept
|
Organelles
|
Concept
|
Liver Neoplasms, Experimental
|
Concept
|
Herpesvirus 1, Human
|
Concept
|
Carcinoma, Neuroendocrine
|
Concept
|
Transducin
|
Concept
|
Trans-Activators
|
Concept
|
Randomized Controlled Trials as Topic
|
Concept
|
Carcinoma, Lewis Lung
|
Concept
|
Cell Culture Techniques
|
Concept
|
Radiopharmaceuticals
|
Concept
|
Caspases
|
Concept
|
Tumor Cells, Cultured
|
Concept
|
rac1 GTP-Binding Protein
|
Concept
|
Focal Adhesions
|
Concept
|
Transforming Growth Factor beta
|
Concept
|
Central Nervous System Neoplasms
|
Concept
|
Vacuolar Proton-Translocating ATPases
|
Concept
|
Cell Adhesion Molecules
|
Concept
|
Lipid Peroxidation
|
Concept
|
Genes, Tumor Suppressor
|
Concept
|
Vinculin
|
Concept
|
Papillomavirus Infections
|
Concept
|
Antigens, CD
|
Concept
|
3T3 Cells
|
Concept
|
Milk Proteins
|
Concept
|
Mitochondria
|
Concept
|
Mortality
|
Concept
|
Leukemia, Myeloid, Acute
|
Concept
|
Chi-Square Distribution
|
Concept
|
Interleukin-8
|
Concept
|
Lymphocytes, Tumor-Infiltrating
|
Concept
|
Culture Media, Conditioned
|
Concept
|
Paclitaxel
|
Concept
|
Proto-Oncogene Proteins c-fos
|
Concept
|
Cytochalasin D
|
Concept
|
Gene Expression
|
Concept
|
Comorbidity
|
Concept
|
Clinical Trials, Phase II as Topic
|
Concept
|
Hematopoietic Cell Growth Factors
|
Concept
|
Case-Control Studies
|
Concept
|
RNA Interference
|
Concept
|
Receptors, Eph Family
|
Concept
|
Prostate-Specific Antigen
|
Concept
|
Receptors, Fibroblast Growth Factor
|
Concept
|
Fractals
|
Concept
|
Meningeal Neoplasms
|
Concept
|
Genes, Reporter
|
Concept
|
Microtubules
|
Concept
|
Paraffin Embedding
|
Concept
|
Myocarditis
|
Concept
|
Angiogenic Proteins
|
Concept
|
Ubiquitin Thiolesterase
|
Concept
|
Interferon-alpha
|
Concept
|
Cholangiocarcinoma
|
Concept
|
Crystallography, X-Ray
|
Concept
|
Receptors, Growth Factor
|
Concept
|
DNA, Complementary
|
Concept
|
Cell Proliferation
|
Concept
|
Chemokines
|
Concept
|
Antigens, CD34
|
Concept
|
Disease Progression
|
Concept
|
ras Proteins
|
Concept
|
Microscopy, Video
|
Concept
|
Proto-Oncogene Proteins c-crk
|
Concept
|
Carcinoma, Ductal, Breast
|
Concept
|
CA-125 Antigen
|
Concept
|
beta Catenin
|
Concept
|
Toll-Like Receptor 3
|
Concept
|
Proto-Oncogene Proteins c-vav
|
Concept
|
Hippocalcin
|
Concept
|
Fluorodeoxyglucose F18
|
Concept
|
Antineoplastic Agents, Alkylating
|
Concept
|
Integrin beta1
|
Concept
|
Angiogenesis Inhibitors
|
Concept
|
GTP-Binding Protein alpha Subunits, Gi-Go
|
Concept
|
Cancer Vaccines
|
Concept
|
Caspase 3
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
Concept
|
Receptors, CXCR4
|
Concept
|
eIF-2 Kinase
|
Concept
|
Chemokine CXCL12
|
Concept
|
src Homology Domains
|
Concept
|
Lipopolysaccharide Receptors
|
Concept
|
Jurkat Cells
|
Concept
|
Protein Tyrosine Phosphatases
|
Concept
|
Pentose Phosphate Pathway
|
Concept
|
Peritoneal Neoplasms
|
Concept
|
In Situ Hybridization, Fluorescence
|
Concept
|
Receptor, ErbB-3
|
Concept
|
Fatal Outcome
|
Concept
|
Topoisomerase I Inhibitors
|
Concept
|
Single-Cell Analysis
|
Concept
|
Ephrin-A2
|
Concept
|
Vascular Endothelial Growth Factor Receptor-2
|
Concept
|
B7-H1 Antigen
|
Concept
|
Green Fluorescent Proteins
|
Concept
|
Systems Biology
|
Concept
|
Integrin beta4
|
Concept
|
Proteomics
|
Concept
|
Vascular Endothelial Growth Factors
|
Concept
|
Cortactin
|
Concept
|
Paired Box Transcription Factors
|
Concept
|
Proteasome Endopeptidase Complex
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
Concept
|
Biological Specimen Banks
|
Concept
|
Carcinoma, Large Cell
|
Concept
|
Carcinoma, Small Cell
|
Concept
|
Area Under Curve
|
Concept
|
COS Cells
|
Concept
|
Proto-Oncogene Proteins c-raf
|
Concept
|
Proto-Oncogene Proteins B-raf
|
Concept
|
Cell Growth Processes
|
Concept
|
Transcription Factor AP-1
|
Concept
|
Proto-Oncogene Proteins c-kit
|
Concept
|
Stem Cell Factor
|
Concept
|
Receptors, Thrombopoietin
|
Concept
|
rac GTP-Binding Proteins
|
Concept
|
Amino Acid Motifs
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
Concept
|
Receptors, Interleukin-8A
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
Concept
|
Bone Morphogenetic Proteins
|
Concept
|
Loss of Heterozygosity
|
Concept
|
Papillomaviridae
|
Concept
|
Fluorescein
|
Concept
|
Interdisciplinary Communication
|
Concept
|
Dynamin II
|
Concept
|
Allelic Imbalance
|
Concept
|
Receptors, Interleukin-8B
|
Concept
|
BRCA2 Protein
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
Concept
|
STAT3 Transcription Factor
|
Concept
|
Proto-Oncogene Proteins c-ret
|
Concept
|
Phloretin
|
Concept
|
Phosphopyruvate Hydratase
|
Concept
|
Phorbol Esters
|
Concept
|
Phosphoric Monoester Hydrolases
|
Concept
|
Platinum
|
Concept
|
Precipitin Tests
|
Concept
|
Promoter Regions, Genetic
|
Concept
|
Chondroitin Sulfate Proteoglycans
|
Concept
|
Focal Adhesion Protein-Tyrosine Kinases
|
Concept
|
Microphthalmia-Associated Transcription Factor
|
Concept
|
Receptors, Notch
|
Concept
|
Hedgehog Proteins
|
Concept
|
Interleukin Receptor Common gamma Subunit
|
Concept
|
DNA Breaks, Double-Stranded
|
Concept
|
Ribs
|
Concept
|
Receptor, EphB4
|
Concept
|
Calgranulin B
|
Concept
|
Stomach Neoplasms
|
Concept
|
Taiwan
|
Concept
|
Technetium
|
Concept
|
Flavanones
|
Concept
|
Testosterone
|
Concept
|
Thrombopoietin
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
Concept
|
Taxoids
|
Concept
|
Meningeal Carcinomatosis
|
Concept
|
Shc Signaling Adaptor Proteins
|
Concept
|
HEK293 Cells
|
Concept
|
Quality Improvement
|
Concept
|
Paxillin
|
Concept
|
SOX9 Transcription Factor
|
Concept
|
PAX5 Transcription Factor
|
Concept
|
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
|
Concept
|
Class I Phosphatidylinositol 3-Kinases
|
Concept
|
Antibodies, Monoclonal, Humanized
|
Concept
|
Human Umbilical Vein Endothelial Cells
|
Concept
|
Insulins
|
Concept
|
Finches
|
Concept
|
Spinal Cord Neoplasms
|
Concept
|
Subcellular Fractions
|
Concept
|
Vanadates
|
Concept
|
Video Recording
|
Concept
|
Adaptor Proteins, Signal Transducing
|
Concept
|
Temperature
|
Concept
|
Zebrafish
|
Concept
|
9,10-Dimethyl-1,2-benzanthracene
|
Concept
|
Blotting, Western
|
Concept
|
Colorectal Neoplasms
|
Concept
|
Protein Interaction Domains and Motifs
|
Concept
|
Small Cell Lung Carcinoma
|
Concept
|
PTEN Phosphohydrolase
|
Concept
|
CDC2 Protein Kinase
|
Concept
|
DNA Copy Number Variations
|
Concept
|
Workload
|
Concept
|
Talin
|
Concept
|
Culture Media, Serum-Free
|
Concept
|
Transcription Factor RelA
|
Concept
|
Tubulin
|
Concept
|
Topoisomerase Inhibitors
|
Concept
|
Survival Rate
|
Concept
|
Multidetector Computed Tomography
|
Concept
|
Receptors, Cytokine
|
Concept
|
Receptors, Interleukin
|
Concept
|
Retinoblastoma Protein
|
Concept
|
Granulocyte Colony-Stimulating Factor
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
Concept
|
ATP-Binding Cassette Transporters
|
Concept
|
Receptor, ErbB-2
|
Concept
|
Thy-1 Antigens
|
Concept
|
CD2 Antigens
|
Concept
|
Genes, src
|
Concept
|
Genes, fos
|
Concept
|
Cell Polarity
|
Concept
|
Spheroids, Cellular
|
Concept
|
Clinical Trials, Phase III as Topic
|
Concept
|
N-Acetylneuraminic Acid
|
Concept
|
DNA Methylation
|
Concept
|
GTP-Binding Proteins
|
Concept
|
Protein Tyrosine Phosphatase, Non-Receptor Type 6
|
Concept
|
Receptors, Chemokine
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
Concept
|
Gene Silencing
|
Concept
|
Carcinoma, Pancreatic Ductal
|
Concept
|
Imaging, Three-Dimensional
|
Concept
|
Xenograft Model Antitumor Assays
|
Concept
|
Receptors, Calcitriol
|
Concept
|
Homeodomain Proteins
|
Concept
|
Tropism
|
Concept
|
Genes, erbB-2
|
Concept
|
HSP90 Heat-Shock Proteins
|
Concept
|
Prostatic Intraepithelial Neoplasia
|
Concept
|
Genistein
|
Concept
|
K562 Cells
|
Concept
|
Neuregulin-1
|
Concept
|
Receptor, EphA2
|
Concept
|
Diabetes Complications
|
Concept
|
Receptors, Lysophosphatidic Acid
|
Concept
|
Crk-Associated Substrate Protein
|
Concept
|
STAT1 Transcription Factor
|
Concept
|
STAT5 Transcription Factor
|
Concept
|
Transcriptome
|
Concept
|
G1 Phase Cell Cycle Checkpoints
|
Concept
|
Keratin-7
|
Concept
|
Keratin-20
|
Concept
|
Janus Kinase 2
|
Concept
|
Precision Medicine
|
Concept
|
Antibodies, Monoclonal, Murine-Derived
|
Concept
|
Molecular Sequence Annotation
|
Concept
|
Ribosomal Protein S6 Kinases, 70-kDa
|
Concept
|
Vascular Endothelial Growth Factor A
|
Concept
|
Programmed Cell Death 1 Receptor
|
Concept
|
Cell Line, Tumor
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p27
|
Concept
|
Ikaros Transcription Factor
|
Concept
|
Forkhead Transcription Factors
|
Concept
|
fms-Like Tyrosine Kinase 3
|
Concept
|
Bovine papillomavirus 1
|
Concept
|
Takotsubo Cardiomyopathy
|
Concept
|
Protein Phosphatase 2
|
Concept
|
Comparative Genomic Hybridization
|
Concept
|
Microvessels
|
Concept
|
Antibodies, Neutralizing
|
Concept
|
Molecular Typing
|
Concept
|
Antineoplastic Agents, Phytogenic
|
Concept
|
Artificial Intelligence
|
Concept
|
Brain Neoplasms
|
Concept
|
Calcium
|
Concept
|
Carbon
|
Concept
|
Carcinoembryonic Antigen
|
Concept
|
Adenocarcinoma, Bronchiolo-Alveolar
|
Concept
|
Cell Line
|
Concept
|
Cells, Cultured
|
Concept
|
Chickens
|
Concept
|
Chromatin
|
Concept
|
Clinical Trials as Topic
|
Concept
|
Deoxycytidine
|
Concept
|
Drug Eruptions
|
Concept
|
Disease Models, Animal
|
Concept
|
Doxorubicin
|
Concept
|
Drug Screening Assays, Antitumor
|
Concept
|
Enhancer Elements, Genetic
|
Concept
|
Epidermal Growth Factor
|
Concept
|
Erythrocytes
|
Concept
|
Esophageal Neoplasms
|
Concept
|
Follow-Up Studies
|
Concept
|
Genetic Testing
|
Concept
|
Injections
|
Concept
|
Lymphocyte Activation
|
Concept
|
Lymphocytes
|
Concept
|
Phosphoric Diester Hydrolases
|
Concept
|
Prospective Studies
|
Concept
|
Pseudopodia
|
Concept
|
Retrospective Studies
|
Concept
|
Serine Endopeptidases
|
Concept
|
T-Lymphocytes
|
Concept
|
Translocation, Genetic
|
Concept
|
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
|
Concept
|
CD4 Antigens
|
Concept
|
Tumor Suppressor Protein p53
|
Concept
|
Granulocyte-Macrophage Colony-Stimulating Factor
|
Concept
|
Cytokines
|
Concept
|
Endothelins
|
Concept
|
Anticarcinogenic Agents
|
Concept
|
Telomere
|
Concept
|
Age of Onset
|
Concept
|
Erythrocyte Transfusion
|
Concept
|
DNA Primers
|
Concept
|
Cystadenocarcinoma, Serous
|
Concept
|
Genes, erbB-1
|
Concept
|
Hyaluronan Receptors
|
Concept
|
Computational Biology
|
Concept
|
Chemokines, CXC
|
Concept
|
Cyclin D1
|
Concept
|
Genetic Predisposition to Disease
|
Concept
|
Epstein-Barr Virus Infections
|
Concept
|
U937 Cells
|
Concept
|
Membrane Microdomains
|
Concept
|
Genomics
|
Concept
|
Collagen Type IV
|
Concept
|
Ephrins
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Concept
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Semaphorins
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Concept
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Vascular Endothelial Growth Factor Receptor-1
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Concept
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Receptors, Lysosphingolipid
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Concept
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Adipokines
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 11
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Concept
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Protein Tyrosine Phosphatase, Non-Receptor Type 12
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Concept
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SOXE Transcription Factors
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Concept
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Molecular Dynamics Simulation
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Academic Article
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p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
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Academic Article
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Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
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Academic Article
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Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
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Academic Article
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p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.
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Academic Article
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The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
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Academic Article
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The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
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Academic Article
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Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
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Academic Article
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The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
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Academic Article
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Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.
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Academic Article
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Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells.
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Academic Article
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Hematopoietic growth factors signal through the formation of reactive oxygen species.
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Academic Article
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Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.
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Academic Article
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The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
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Academic Article
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Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
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Academic Article
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Role of serum tumor markers CA 125 and CEA in non-small cell lung cancer.
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Academic Article
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The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
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Academic Article
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The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
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Academic Article
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Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
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Academic Article
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Cancer-associated retinopathy in a patient with non-small-cell lung carcinoma.
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Academic Article
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Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines.
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Academic Article
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Gemcitabine and vinorelbine in patients with advanced lung cancer: preclinical studies and report of a phase I trial.
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Academic Article
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Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
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Academic Article
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The noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo.
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Academic Article
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A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.
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Academic Article
|
ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction.
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Academic Article
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Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
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Academic Article
|
A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration.
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Academic Article
|
Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.
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Academic Article
|
SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
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Academic Article
|
BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.
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Academic Article
|
Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
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Academic Article
|
CD2 molecules redistribute to the uropod during T cell scanning: implications for cellular activation and immune surveillance.
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Academic Article
|
Role of the cytoskeletal protein paxillin in oncogenesis.
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Academic Article
|
Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
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Academic Article
|
Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.
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Academic Article
|
Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
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Academic Article
|
Circulating tumor cells and serum tumor biomarkers in small cell lung cancer.
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Academic Article
|
Cell motility, adhesion, homing, and migration assays in the studies of tyrosine kinases.
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Academic Article
|
Role of receptor tyrosine kinases in lung cancer.
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Academic Article
|
Gemcitabine-induced radiation recall.
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Academic Article
|
Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer.
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Academic Article
|
Flow cytometric determination of lipid peroxidation using fluoresceinated phosphoethanolamine.
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Academic Article
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c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
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Academic Article
|
Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer.
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Academic Article
|
2-methoxyestradiol alters cell motility, migration, and adhesion.
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Academic Article
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Molecular alterations in lung cancer. Impact on prognosis.
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Academic Article
|
Small cell lung cancer: from molecular biology to novel therapeutics.
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Academic Article
|
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
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Academic Article
|
Use of cytokeratins 7 and 20 in determining the origin of metastatic carcinoma of unknown primary, with special emphasis on lung cancer.
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Academic Article
|
Targeted molecules in small cell lung cancer.
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Academic Article
|
Small-cell cancers, and an unusual reaction to chemotherapy. Case 1. Extrapulmonary small-cell carcinoma arising in the prostate.
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Academic Article
|
Targeting c-Kit mutations: basic science to novel therapies.
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Academic Article
|
p53 and Bcl-2 in small cell-lung cancer.
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Academic Article
|
Reliable and sensitive identification of occult tumor cells using the improved rare event imaging system.
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Academic Article
|
Phase II study of imatinib in patients with small cell lung cancer.
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Academic Article
|
Therapeutic targeting of the receptor tyrosine kinase Met.
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Academic Article
|
A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
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Academic Article
|
Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer.
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Academic Article
|
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
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Academic Article
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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
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Academic Article
|
Novel therapies in lung cancer.
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Academic Article
|
Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2.
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Academic Article
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
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Academic Article
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A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
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Academic Article
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Molecular biology of malignant mesothelioma: a review.
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Academic Article
|
Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer.
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Academic Article
|
c-Met inhibition.
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Academic Article
|
Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
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Academic Article
|
A review of topoisomerase inhibition in lung cancer.
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Academic Article
|
c-Met: structure, functions and potential for therapeutic inhibition.
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Academic Article
|
Recent advances in the molecular biology, diagnosis and novel therapies for various small blue cell tumors.
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Academic Article
|
Lung carcinoma in African Americans.
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Academic Article
|
c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy.
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Academic Article
|
Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: a trial of the Chicago, PMH, and California Phase II Consortia.
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Academic Article
|
Vitamin D receptor expression in normal, premalignant, and malignant human lung tissue.
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Academic Article
|
PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
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Academic Article
|
MET as a target for treatment of chest tumors.
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Academic Article
|
Phase I trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer.
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Academic Article
|
Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.
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Academic Article
|
Protein kinase C beta in malignant pleural mesothelioma.
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Academic Article
|
EGFR-targeted therapeutics: focus on SCCHN and NSCLC.
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Academic Article
|
Biology and novel therapeutics for neuroendocrine tumors of the lung.
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Academic Article
|
Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
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Academic Article
|
The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
|
Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
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Academic Article
|
Meta-analysis: surveillance with ultrasound for early-stage hepatocellular carcinoma in patients with cirrhosis.
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Academic Article
|
Receptor tyrosine kinases and inhibitors in lung cancer.
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Academic Article
|
Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer.
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Academic Article
|
The role of ephrins and Eph receptors in cancer.
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Academic Article
|
Concerted potent humoral immune responses to autoantigens are associated with tumor destruction and favorable clinical outcomes without autoimmunity.
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Academic Article
|
Expression and mutational analysis of MET in human solid cancers.
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Academic Article
|
Stamp out lung cancer.
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Academic Article
|
MET pathway as a therapeutic target.
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Academic Article
|
Role of c-Met in cancer: emphasis on lung cancer.
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Academic Article
|
EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
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Academic Article
|
Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation.
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Academic Article
|
Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
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Academic Article
|
PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
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Academic Article
|
MET receptor tyrosine kinase.
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Academic Article
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Ethnic differences and functional analysis of MET mutations in lung cancer.
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Academic Article
|
The role of chemokine receptor CXCR4 in lung cancer.
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Academic Article
|
Fyn: a novel molecular target in cancer.
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Academic Article
|
Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors.
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Academic Article
|
CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
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Academic Article
|
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
|
The clinical presentation and prognostic factors for intrahepatic and extrahepatic cholangiocarcinoma in a tertiary care centre.
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Academic Article
|
Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
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Academic Article
|
The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation.
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Academic Article
|
Chemotherapy and high dose radiotherapy followed by resection for locally advanced nonsmall cell lung cancers.
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Academic Article
|
Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
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Academic Article
|
Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.
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Academic Article
|
Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
|
Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
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Academic Article
|
Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database.
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Academic Article
|
Pathologic response rates following definitive dose image-guided chemoradiotherapy and resection for locally advanced non-small cell lung cancer.
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Academic Article
|
Non-receptor tyrosine kinase inhibitors in lung cancer.
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Academic Article
|
FYN is overexpressed in human prostate cancer.
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Academic Article
|
Takotsubo cardiomyopathy in a patient with squamous cell esophageal carcinoma.
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Academic Article
|
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
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Academic Article
|
Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
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Academic Article
|
Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.
|
Academic Article
|
Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.
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Academic Article
|
Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
|
Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
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Academic Article
|
A novel classification of lung cancer into molecular subtypes.
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Academic Article
|
Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer.
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Academic Article
|
Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
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Academic Article
|
Differential expression of RON in small and non-small cell lung cancers.
|
Academic Article
|
Mind-mapping for lung cancer: towards a personalized therapeutics approach.
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Academic Article
|
PAX3 and SOX10 activate MET receptor expression in melanoma.
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Academic Article
|
Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma.
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Academic Article
|
Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer.
|
Academic Article
|
Bortezomib for patients with advanced-stage bronchioloalveolar carcinoma: a California Cancer Consortium Phase II study (NCI 7003).
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Academic Article
|
Hemostatic abnormalities in untreated cancer: incidence and correlation with thrombotic and hemorrhagic complications.
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Academic Article
|
Therapeutic targeting of receptor tyrosine kinases in lung cancer.
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Academic Article
|
The effects of monensin on membrane lipids of cultured human skin fibroblasts.
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Academic Article
|
Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
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Academic Article
|
Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
|
Academic Article
|
MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
|
Academic Article
|
Multicenter phase II trial of Motexafin gadolinium and pemetrexed for second-line treatment in patients with non-small cell lung cancer.
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Academic Article
|
MET and phosphorylated MET as potential biomarkers in lung cancer.
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Academic Article
|
The database of chromosome imbalance regions and genes resided in lung cancer from Asian and Caucasian identified by array-comparative genomic hybridization.
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Academic Article
|
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
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Academic Article
|
CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer.
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Academic Article
|
Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
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Academic Article
|
Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions.
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Academic Article
|
Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
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Academic Article
|
Phase 2 trial of Linifanib (ABT-869) in patients with advanced non-small cell lung cancer.
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Academic Article
|
Diffuse alveolar damage after a single dose of topotecan in a patient with pulmonary fibrosis and small cell lung cancer.
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Academic Article
|
The role of the c-Met pathway in lung cancer and the potential for targeted therapy.
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Academic Article
|
Control of bleeding in patients with immune and nonimmune thrombocytopenia with aminocaproic acid.
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Academic Article
|
Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
|
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
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Academic Article
|
Targeted and cytotoxic therapy in coordinated sequence (TACTICS): erlotinib, bevacizumab, and standard chemotherapy for non-small-cell lung cancer, a phase II trial.
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Academic Article
|
Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer.
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Academic Article
|
Tyrosine kinase mutations in human cancer.
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Academic Article
|
Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.
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Academic Article
|
c-Met is a potentially new therapeutic target for treatment of human melanoma.
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Academic Article
|
CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells.
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Academic Article
|
Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
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Academic Article
|
The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
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Academic Article
|
Pneumonia and infraorbital abscess in a 29-year-old diabetic pregnant woman.
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Academic Article
|
Altered membrane fluidity in rat hepatocytes during endotoxic shock.
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Academic Article
|
Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
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Academic Article
|
Review of clinic trials: agents targeting c-Met.
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Academic Article
|
MET molecular mechanisms and therapies in lung cancer.
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Academic Article
|
Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
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Academic Article
|
NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
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Academic Article
|
Generation of comprehensive thoracic oncology database--tool for translational research.
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Academic Article
|
Personalized treatment of lung cancer.
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Academic Article
|
An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
|
Academic Article
|
Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
|
Academic Article
|
Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer.
|
Academic Article
|
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
|
Academic Article
|
Development of The American Association for Thoracic Surgery guidelines for low-dose computed tomography scans to screen for lung cancer in North America: recommendations of The American Association for Thoracic Surgery Task Force for Lung Cancer Screening and Surveillance.
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Academic Article
|
The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups.
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Academic Article
|
Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer.
|
Academic Article
|
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study.
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Academic Article
|
Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
|
Academic Article
|
Three-dimensional stereoscopic volume rendering of malignant pleural mesothelioma.
|
Academic Article
|
Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1).
|
Academic Article
|
Involvement of the adapter protein CRKL in integrin-mediated adhesion.
|
Academic Article
|
Case 1: small bowel obstruction due to metastatic lung cancer.
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Academic Article
|
Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
|
Academic Article
|
Detection and analysis of lung cancer cells from body fluids using a rare event imaging system.
|
Academic Article
|
Molecular and cellular biology of small cell lung cancer.
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Academic Article
|
Unusual problems in breast cancer and a rare lung cancer case. Case 4. Primary lymphoepithelioma-like carcinoma of the lung.
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Academic Article
|
A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
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Academic Article
|
Mechanisms of metastasis as related to receptor tyrosine kinases in small-cell lung cancer.
|
Academic Article
|
Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer.
|
Academic Article
|
A phase I study of pemetrexed, carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer.
|
Academic Article
|
Key signaling pathways and targets in lung cancer therapy.
|
Academic Article
|
Biomarker discovery in lung cancer--promises and challenges of clinical proteomics.
|
Academic Article
|
CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
|
Academic Article
|
C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
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Academic Article
|
Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
|
Academic Article
|
Nephrogenic systemic fibrosis associated with stromal and vascular calcification, report of two cases.
|
Academic Article
|
Novel targets for therapeutic agents in small cell lung cancer.
|
Academic Article
|
The role of EGFR inhibition in the treatment of non-small cell lung cancer.
|
Academic Article
|
MET/PKCbeta expression correlate with metastasis and inhibition is synergistic in lung cancer.
|
Academic Article
|
Phase II study of amrubicin as second-line therapy in patients with platinum-refractory small-cell lung cancer.
|
Academic Article
|
Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung.
|
Academic Article
|
Paxillin expression and amplification in early lung lesions of high-risk patients, lung adenocarcinoma and metastatic disease.
|
Academic Article
|
RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
|
Academic Article
|
Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
|
Academic Article
|
Role of MetMAb (OA-5D5) in c-MET active lung malignancies.
|
Academic Article
|
A phase I trial of pan-Bcl-2 antagonist obatoclax administered as a 3-h or a 24-h infusion in combination with carboplatin and etoposide in patients with extensive-stage small cell lung cancer.
|
Academic Article
|
Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.
|
Academic Article
|
Quality of life after radical pleurectomy decortication for malignant pleural mesothelioma.
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Academic Article
|
Utilisation of a thoracic oncology database to capture radiological and pathological images for evaluation of response to chemotherapy in patients with malignant pleural mesothelioma.
|
Academic Article
|
Degradation and regurgitation of extracellular proteins by cultured mouse peritoneal macrophages and baby hamster kidney fibroblasts. Kinetic evidence that the transfer of proteins to lysosomes is not irreversible.
|
Academic Article
|
Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
|
Academic Article
|
Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
|
Academic Article
|
Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
|
Academic Article
|
The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
|
Academic Article
|
Evidence-based role of bevacizumab in non-small cell lung cancer.
|
Academic Article
|
A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer.
|
Academic Article
|
MET as a possible target for non-small-cell lung cancer.
|
Academic Article
|
Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
|
Academic Article
|
Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer.
|
Academic Article
|
Etoposide and temozolomide in combination for the treatment of progressive small-cell lung cancer central nervous system metastases: two cases.
|
Academic Article
|
Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
|
Academic Article
|
EphB4 as a therapeutic target in mesothelioma.
|
Academic Article
|
TLR3 agonists and proinflammatory antitumor activities.
|
Academic Article
|
Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
|
Academic Article
|
Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
|
Academic Article
|
Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
|
Academic Article
|
Teaching Video NeuroImages: myokymia and nerve hyperexcitability as components of Morvan syndrome due to malignant thymoma.
|
Academic Article
|
Targeted agents in non-small cell lung cancer therapy: What is there on the horizon?
|
Academic Article
|
Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.
|
Academic Article
|
Increased µ-opioid receptor expression in metastatic lung cancer.
|
Academic Article
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The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer.
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Academic Article
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Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
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Academic Article
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Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
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Academic Article
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Molecular biomarkers for future screening of lung cancer.
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Academic Article
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Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.
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Academic Article
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Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic.
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Academic Article
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MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
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Academic Article
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Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
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Academic Article
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Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.
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Academic Article
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Crizotinib in ROS1-rearranged non-small-cell lung cancer.
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Academic Article
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Leptomeningeal carcinomatosis in esophageal cancer: a case series and systematic review of the literature.
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Academic Article
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Brain metastases in non-small-cell lung cancer: better outcomes through current therapies and utilization of molecularly targeted approaches.
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Academic Article
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Mitochondrial dynamics: biology and therapy in lung cancer.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
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Academic Article
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Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
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Academic Article
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O-6-methylguanine-deoxyribonucleic acid methyltransferase methylation enhances response to temozolomide treatment in esophageal cancer.
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Academic Article
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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
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Academic Article
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Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.
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Academic Article
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Molecular pathways and therapeutic targets in lung cancer.
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Academic Article
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Temozolomide and/or Erlotinib in the Treatment of Lung Cancer Patients With Progressive Central Nervous System Metastases.
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Academic Article
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Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer.
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Academic Article
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Evaluation of a novel rash scale and a serum proteomic predictor in a randomized phase II trial of sequential or concurrent cetuximab and pemetrexed in previously treated non-small cell lung cancer.
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Academic Article
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The educational impact of the Specialty Care Access Network-Extension of Community Healthcare Outcomes program.
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Academic Article
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Geographic variation in radiologist capacity and widespread implementation of lung cancer CT screening.
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Academic Article
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Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
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Academic Article
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Phase I dose-escalation study of onartuzumab as a single agent and in combination with bevacizumab in patients with advanced solid malignancies.
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Academic Article
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A personalized treatment for lung cancer: molecular pathways, targeted therapies, and genomic characterization.
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Academic Article
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A new hope for precision medicine.
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Academic Article
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Biomarkers in lung cancer: from early detection to novel therapeutics and decision making.
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Academic Article
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AXL mediates resistance to cetuximab therapy.
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Academic Article
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Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
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Academic Article
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A safety assessment of crizotinib in the treatment of ALK-positive NSCLC patients.
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Academic Article
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A multicenter phase I study of pazopanib in combination with paclitaxel in first-line treatment of patients with advanced solid tumors.
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Academic Article
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Molecularly targeted therapies in non-small-cell lung cancer annual update 2014.
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Academic Article
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Diagnostic challenges in non-small-cell lung cancer: an integrated medicine approach.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
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Academic Article
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AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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A new PET/CT volumetric prognostic index for non-small cell lung cancer.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
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Academic Article
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Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
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Academic Article
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Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.
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Academic Article
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HABP2 is a Novel Regulator of Hyaluronan-Mediated Human Lung Cancer Progression.
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Academic Article
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MET as a drug target.
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Academic Article
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
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Academic Article
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Phase II Study of the AKT Inhibitor MK-2206 plus Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Who Previously Progressed on Erlotinib.
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Academic Article
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Whole-animal mounts of Caenorhabditis elegans for 3D imaging using atomic force microscopy.
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Academic Article
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Lung cancer-a fractal viewpoint.
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Academic Article
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ROS1 rearranged non-small cell lung cancer brain metastases respond to low dose radiotherapy.
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Academic Article
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Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer.
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Academic Article
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Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.
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Academic Article
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C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
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Academic Article
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Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer.
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Academic Article
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Systemic therapies in the treatment of non-small-cell lung cancer brain metastases.
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Academic Article
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Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
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Academic Article
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Concurrent EGFR Mutation and ALK Translocation in Non-Small Cell Lung Cancer.
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Academic Article
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Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
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Academic Article
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The Chicago Thoracic Oncology Database Consortium: A Multisite Database Initiative.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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1330: Brigatinib efficacy and safety in patients (Pts) with anaplastic lymphoma kinase (ALK)-positive (ALK+) non-small cell lung cancer (NSCLC) in a phase 1/2 trial.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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Tumor Heterogeneity and Therapeutic Resistance.
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Academic Article
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Prognostic and Predictive Value in KRAS in Non-Small-Cell Lung Cancer: A Review.
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Academic Article
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Mutation testing for directing upfront targeted therapy and post-progression combination therapy strategies in lung adenocarcinoma.
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Academic Article
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Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.
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Academic Article
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Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation.
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Academic Article
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Post-crizotinib management of effective ceritinib therapy in a patient with ALK-positive non-small cell lung cancer.
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Academic Article
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FAK and paxillin, two potential targets in pancreatic cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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MET in the Driver's Seat: Exon 14 Skipping Mutations as Actionable Targets in Lung Cancer.
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Academic Article
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Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
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Academic Article
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PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
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Academic Article
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The MET axis as a therapeutic target.
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Academic Article
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Crizotinib (PF02341066) as a ALK /MET inhibitor- Special Emphasis as a Therapeutic Drug Against Lung Cancer.
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Academic Article
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DIFFERENTIAL SERUM LEVEL OF SPECIFIC HAPTOGLOBIN ISOFORMS IN SMALL CELL LUNG CANCER.
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Academic Article
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KRAS in Non-Small-Cell Lung Cancer-Reply.
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Academic Article
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Unique metastases of ALK mutated lung cancer activated to the adnexa of the uterus.
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Academic Article
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Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial.
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Academic Article
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Genomic mutation-driven metastatic breast cancer therapy: a single center experience.
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Academic Article
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RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
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Academic Article
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Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.
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Academic Article
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A phase I dose-escalating study of combination pemetrexed-based chemotherapy and concomitant radiotherapy for locally advanced or metastatic non-small cell lung or esophageal cancer.
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Academic Article
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Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
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Academic Article
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CALGB 30103: A randomized phase II study of carboplatin and etoposide (CE) with or without G3139 in patients with extensive stage small cell lung cancer (ES-SCLC).
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Academic Article
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A phase I study of XL184, a RET, VEGFR2, and MET kinase inhibitor, in patients (pts) with advanced malignancies, including pts with medullary thyroid cancer (MTC).
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Academic Article
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Refining epidermal growth factor receptor (EGFR) -inhibition-related rash (EIRR) phenotypes with a cetuximab (C) monotherapy stage of a phase II trial for non-small cell lung cancer (NSCLC).
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Academic Article
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Development of response criteria for mesothelioma based on a mathematical model.
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Academic Article
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A phase 1/2 study of STA-4783 in combination with paclitaxel and carboplatin in chemo-naïve advanced non-small cell lung cancer (NSCLC).
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Academic Article
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Phase 2 trial of talabostat and docetaxel in patients with stage IIIb/IV NSCLC.
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Academic Article
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Phase II trial of sequential bevacizumab (B), erlotinib (E) and chemotherapy for first line treatment of clinical stage IIIB or IV non-small cell lung cancer (NSCLC).
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Academic Article
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Activity of XL647 in clinically selected NSCLC patients (pts) enriched for the presence of EGFR mutations: Results from Phase 2.
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Academic Article
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A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
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Academic Article
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Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
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Academic Article
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The accelerated path of ceritinib: Translating pre-clinical development into clinical efficacy.
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Academic Article
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
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Academic Article
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Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
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Academic Article
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Value-Based Medicine and Integration of Tumor Biology.
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Academic Article
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Canonical and alternative transcript expression of PAX6 and CXCR4 in pancreatic cancer.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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Capecitabine and Celecoxib as a Promising Therapy for Thymic Neoplasms.
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Academic Article
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Complete Pathologic Response When Adding Pembrolizumab to Neoadjuvant Chemotherapy in Stage IIIA Non-Small-Cell Lung Cancer.
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Academic Article
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2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer.
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Academic Article
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Effective osimertinib treatment in a patient with discordant T790Â M mutation detection between liquid biopsy and tissue biopsy.
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Academic Article
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Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
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Academic Article
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Current and Future Management of Malignant Mesothelioma: A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Applied Research Foundation.
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Academic Article
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Correction: AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target.
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Academic Article
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Phase 1 Study of Accelerated Hypofractionated Radiation Therapy With Concurrent Chemotherapy for Stage III Non-Small Cell Lung Cancer: CALGB 31102 (Alliance).
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Academic Article
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The Genetic/Non-genetic Duality of Drug 'Resistance' in Cancer.
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Academic Article
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Correction: Genomic mutation-driven metastatic breast cancer therapy: a single center experience.
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Academic Article
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Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.
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Academic Article
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2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells.
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Academic Article
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Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations.
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Academic Article
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EphB4: A promising target for upper aerodigestive malignancies.
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Academic Article
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Stereotactic body radiation therapy (SBRT) for early-stage lung cancer in the elderly.
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Academic Article
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Modeling small cell lung cancer (SCLC) biology through deterministic and stochastic mathematical models.
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Academic Article
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2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
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Academic Article
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A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors.
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Academic Article
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Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
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Academic Article
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Managing Patients With Relapsed Small-Cell Lung Cancer.
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Academic Article
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Empowering survivors after colorectal and lung cancer treatment: Pilot study of a Self-Management Survivorship Care Planning intervention.
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Academic Article
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The brigatinib experience: a new generation of therapy for ALK-positive non-small-cell lung cancer.
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Academic Article
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Untying the gordion knot of targeting MET in cancer.
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Academic Article
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Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients.
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Academic Article
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Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
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Academic Article
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Heuristic value-based framework for lung cancer decision-making.
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Academic Article
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B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
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Academic Article
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State-of-the-art considerations in small cell lung cancer brain metastases.
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Academic Article
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Responses to Alectinib in ALK-rearranged Papillary Renal Cell Carcinoma.
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Academic Article
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A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer.
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Academic Article
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Value-based genomics.
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Academic Article
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Combination systemic therapies with immune checkpoint inhibitors in pancreatic cancer: overcoming resistance to single-agent checkpoint blockade.
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Academic Article
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Inhibiting crosstalk between MET signaling and mitochondrial dynamics and morphology: a novel therapeutic approach for lung cancer and mesothelioma.
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Academic Article
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The DNA walk and its demonstration of deterministic chaos-relevance to genomic alterations in lung cancer.
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Academic Article
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RLIP inhibition suppresses breast-to-lung metastasis.
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Academic Article
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Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.
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Academic Article
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RLIP: An existential requirement for breast carcinogenesis.
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Academic Article
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Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level.
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Academic Article
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The gut microbiome and response to immune checkpoint inhibitors: preclinical and clinical strategies.
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Academic Article
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Correction: Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-negative Breast Cancer.
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Academic Article
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Combined Checkpoint Inhibition and Chemotherapy: New Era of 1st-Line Treatment for Non-Small-Cell Lung Cancer.
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Academic Article
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Early mortality of stage IV non-small cell lung cancer in the United States.
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Academic Article
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Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
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Academic Article
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Optimal adjuvant therapy in clinically N2 non-small cell lung cancer patients undergoing neoadjuvant chemotherapy and surgery: The importance of pathological response and lymph node ratio.
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Academic Article
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Targeted Therapies in Non-small-Cell Lung Cancer.
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Academic Article
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Pathologic Considerations and Standardization in Mesothelioma Clinical Trials.
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Academic Article
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Prolonged Pharmacokinetic Interaction Between Capecitabine and a CYP2C9 Substrate, Celecoxib.
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Academic Article
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Small Cell Lung Cancer Therapeutic Responses Through Fractal Measurements: From Radiology to Mitochondrial Biology.
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Academic Article
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Notch signaling in breast cancer: From pathway analysis to therapy.
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Academic Article
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The Mitochondrion as an Emerging Therapeutic Target in Cancer.
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Academic Article
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Patterns of Biomarker Testing Rates and Appropriate Use of Targeted Therapy in the First-Line, Metastatic Non-Small Cell Lung Cancer Treatment Setting.
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Academic Article
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Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting.
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Academic Article
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EPHA2 mutations with oncogenic characteristics in squamous cell lung cancer and malignant pleural mesothelioma.
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Academic Article
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Monitoring and Determining Mitochondrial Network Parameters in Live Lung Cancer Cells.
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Academic Article
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Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS.
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Academic Article
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USP22 Interacts with PALB2 and Promotes Chemotherapy Resistance via Homologous Recombination of DNA Double-Strand Breaks.
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Academic Article
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Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.
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Academic Article
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Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
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Academic Article
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RLIP controls receptor-ligand signaling by regulating clathrin-dependent endocytosis.
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Academic Article
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SOX9: The master regulator of cell fate in breast cancer.
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Academic Article
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Presence and structure-activity relationship of intrinsically disordered regions across mucins.
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Academic Article
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Precision medicine and actionable alterations in lung cancer: A single institution experience.
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Academic Article
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Association of TGF-ß1 Polymorphisms with Breast Cancer Risk: A Meta-Analysis of Case-Control Studies †.
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Academic Article
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Radiomic prediction of mutation status based on MR imaging of lung cancer brain metastases.
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Academic Article
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Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti-c-Met Antibody, in Patients with Advanced Solid Tumors.
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Academic Article
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Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
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Academic Article
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The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
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Academic Article
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Therapeutic targeting of miRNA-216b in cancer.
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Academic Article
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Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
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Academic Article
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Opportunities for improving cancer treatment using systems biology.
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Academic Article
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The role of EGFR mutations in predicting recurrence in early and locally advanced lung adenocarcinoma following definitive therapy.
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Academic Article
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
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Academic Article
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Implementing Lung Cancer Screening and Prevention in Academic Centers, Affiliated Network Offices and Collaborating Care Sites.
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Academic Article
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Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors.
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Academic Article
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Non-Small Cell Lung Cancer from Genomics to Therapeutics: A Framework for Community Practice Integration to Arrive at Personalized Therapy Strategies.
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Academic Article
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Complex Oncological Decision-Making Utilizing Fast-and-Frugal Trees in a Community Setting-Role of Academic and Hybrid Modeling.
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Academic Article
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MET receptor in oncology: From biomarker to therapeutic target.
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Academic Article
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Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer.
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Academic Article
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Progressive Neurologic Changes in a Patient With Metastatic Non-Small-Cell Lung Cancer: Cancer Effects or a Secondary Diagnosis?
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Academic Article
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Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics.
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Academic Article
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Small Cell Lung Cancer from Traditional to Innovative Therapeutics: Building a Comprehensive Network to Optimize Clinical and Translational Research.
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Academic Article
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Integrating Clinical and Translational Research Networks-Building Team Medicine.
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Academic Article
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A Non-genetic Mechanism Involving the Integrin ß4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
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Academic Article
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The Effects of Time to Treatment Initiation for Patients With Non-small-cell Lung Cancer in the United States.
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Academic Article
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Activation of EPHA2-ROBO1 Heterodimer by SLIT2 Attenuates Non-canonical Signaling and Proliferation in Squamous Cell Carcinomas.
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Academic Article
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Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease.
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Academic Article
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Erratum: A Non-genetic Mechanism Involving the Integrin ß4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer.
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Academic Article
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Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC patient with high PD-L1 and STK11: A case report.
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Academic Article
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Role of immunotherapy and co-mutations on KRAS-mutant non-small cell lung cancer survival.
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Academic Article
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Rapid progression of disease from immunotherapy following targeted therapy: insights into treatment management and sequence.
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Academic Article
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Prolonged survival and response to tepotinib in a non-small-cell lung cancer patient with brain metastases harboring MET exon 14 mutation: a research report.
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Academic Article
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Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy.
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Academic Article
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Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).
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Academic Article
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Acquired Resistance to PD-1/PD-L1 Blockade in Lung Cancer: Mechanisms and Patterns of Failure.
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Academic Article
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Integrating Academic and Community Cancer Care and Research through Multidisciplinary Oncology Pathways for Value-Based Care: A Review and the City of Hope Experience.
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Academic Article
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Co-stimulatory and co-inhibitory immune markers in solid tumors with MET alterations.
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Academic Article
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Activating p53 function by targeting RLIP.
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Academic Article
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Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP.
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Academic Article
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The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC).
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Academic Article
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Durvalumab for Stage III EGFR-Mutated NSCLC After Definitive Chemoradiotherapy.
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Academic Article
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Group Behavior and Emergence of Cancer Drug Resistance.
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Academic Article
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RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
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Academic Article
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Therapeutic Potential of Olaparib in Combination With Pembrolizumab in a Young Patient With a Maternally Inherited BRCA2 Germline Variant: A Research Report.
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Academic Article
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Quantifying Cancer: More Than Just a Numbers Game.
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Academic Article
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Improving Care for Patients With Stage III or IV NSCLC: Learnings for Multidisciplinary Teams From the ACCC National Quality Survey.
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Academic Article
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Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy.
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Academic Article
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Disparate outcomes in nonsmall cell lung cancer by immigration status.
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Academic Article
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RNA-based therapies: A cog in the wheel of lung cancer defense.
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Academic Article
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Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors.
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Academic Article
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Predicting Survival Duration With MRI Radiomics of Brain Metastases From Non-small Cell Lung Cancer.
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Academic Article
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ST6GalNAc-I promotes lung cancer metastasis by altering MUC5AC sialylation.
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Academic Article
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Germline mutations and age at onset of lung adenocarcinoma.
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Academic Article
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Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.
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Academic Article
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The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin ß-Like 1-ß-Catenin Protein Complex.
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Academic Article
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Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer.
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Academic Article
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MicroRNA-1: Diverse role of a small player in multiple cancers.
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Academic Article
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Molecular and Clinical Features of Hospital Admissions in Patients with Thoracic Malignancies on Immune Checkpoint Inhibitors.
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Academic Article
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The Association between Polluted Neighborhoods and TP53-Mutated Non-Small Cell Lung Cancer.
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Academic Article
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Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
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Academic Article
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Targeting the mercapturic acid pathway for the treatment of melanoma.
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Academic Article
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Evaluation of Somatic Mutations in Solid Metastatic Pan-Cancer Patients.
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Academic Article
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Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
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Academic Article
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Immunotherapy in Non-Small Cell Lung Cancer Patients with Brain Metastases: Clinical Challenges and Future Directions.
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Academic Article
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Elevated Eosinophil Count Following Pembrolizumab Treatment for Non-Small Cell Lung Cancer.
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Academic Article
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Immune Checkpoint Inhibitor-Induced Myocarditis with Myositis/Myasthenia Gravis Overlap Syndrome: A Systematic Review of Cases.
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Academic Article
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Twitter as a Tool to Spread Communication Regarding Genitourinary Cancers During the COVID-19 Pandemic.
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Academic Article
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Near-Complete Response to Combined Pembrolizumab and Platinum-Doublet in a Patient With STK11/KRAS Mutated Advanced Lung Adenocarcinoma.
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Academic Article
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Targeting CA-125 Transcription by Development of a Conditionally Replicative Adenovirus for Ovarian Cancer Treatment.
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Academic Article
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JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes-Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies.
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Academic Article
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Response.
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Academic Article
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Biologically Active Volume of Disease (BaVD) Predicts for Survival in Metastatic Non-Small Cell Lung Cancer.
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Academic Article
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Retraction.
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Academic Article
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Infectious complications of immune checkpoint inhibitors in solid organ malignancies.
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Academic Article
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Patterns of Care in Maintenance Therapy in US Patients Undergoing Definitive Chemoradiation for Stage 3 Non-Small Cell Lung Cancer (NSCLC).
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Academic Article
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ALK-Directed Therapy in Non-NSCLC Malignancies: Are We Ready?
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Academic Article
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Co-opting disorder into order: Intrinsically disordered proteins and the early evolution of complex multicellularity.
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Academic Article
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The next targets for small cell lung cancer.
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Academic Article
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Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy.
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Academic Article
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Protein conformational dynamics and phenotypic switching.
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Academic Article
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Postoperative Radiation Therapy Should Be Used for Completely Resected Stage III-N2 NSCLC in Select Patients.
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Academic Article
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Novel Therapeutic Targets and Immune Dysfunction in Malignant Pleural Mesothelioma.
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Academic Article
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Intrinsically Disordered Proteins: Critical Components of the Wetware.
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Academic Article
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Correction: 2'-Hydroxyflavanone effectively targets RLIP76-mediated drug transport and regulates critical signaling networks in breast cancer.
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Academic Article
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Small Cell Lung Cancer Transformation following Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
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Academic Article
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AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer.
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Academic Article
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Correction: Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
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Academic Article
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Report of the First International Symposium on NUT Carcinoma.
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Academic Article
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Machine learning to refine prognostic and predictive nodal burden thresholds for post-operative radiotherapy in completely resected stage III-N2 non-small cell lung cancer.
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Academic Article
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Intrinsic disorder, extraterrestrial peptides, and prebiotic life on the earth.
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Academic Article
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Endothelin-axis antagonism enhances tumor perfusion in pancreatic cancer.
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Academic Article
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Chemokines and NSCLC: Emerging role in prognosis, heterogeneity, and therapeutics.
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Academic Article
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Ablative Radiotherapy as a Strategy to Overcome TKI Resistance in EGFR-Mutated NSCLC.
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Academic Article
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Leveraging deep learning algorithms for synthetic data generation to design and analyze biological networks.
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Academic Article
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Exploring the Next Frontier in Non-Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor Receptor.
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Academic Article
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MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
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Academic Article
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Addressing Drug Resistance in Cancer: A Team Medicine Approach.
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Academic Article
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Neighborhood disadvantage is associated with KRAS-mutated non-small cell lung cancer risk.
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Academic Article
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Utilization of model-agnostic explainable artificial intelligence frameworks in oncology: a narrative review.
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Academic Article
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Addressing the genetic/nongenetic duality in cancer with systems biology.
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Academic Article
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A Systems Biology Approach for Addressing Cisplatin Resistance in Non-Small Cell Lung Cancer.
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Academic Article
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Intrinsically disordered BMP4 morphogen and the beak of the finch: Co-option of an ancient axial patterning system.
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Academic Article
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An Updated Review on Radiation Treatment Management in Thymus Cancers.
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Academic Article
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Increasing clinician participation in tobacco cessation by an implementation science-based tobacco cessation champion program.
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Academic Article
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Pyramidal Decision Support Framework Leverages Subspecialty Expertise across Enterprise to Achieve Superior Cancer Outcomes and Personalized, Precision Care Plans.
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Academic Article
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Clinical and Molecular Features of KRAS-Mutated Lung Cancer Patients Treated with Immune Checkpoint Inhibitors.
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Academic Article
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RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling.
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Academic Article
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Prognostic significance of natural products against multidrug tumor resistance.
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Academic Article
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Integration of artificial intelligence in lung cancer: Rise of the machine.
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Academic Article
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Precision oncology provides opportunities for targeting KRAS-inhibitor resistance.
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Academic Article
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Prognostic Role of Biologically Active Volume of Disease in Patients With Metastatic Lung Adenocarcinoma.
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Academic Article
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Overcoming Barriers to Tobacco Cessation and Lung Cancer Screening among Racial and Ethnic Minority Groups and Underserved Patients in Academic Centers and Community Network Sites: The City of Hope Experience.
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Academic Article
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Predicting survival of NSCLC patients treated with immune checkpoint inhibitors: Impact and timing of immune-related adverse events and prior tyrosine kinase inhibitor therapy.
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Academic Article
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Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study.
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Academic Article
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Assessment of Barriers and Challenges to Screening, Diagnosis, and Biomarker Testing in Early-Stage Lung Cancer.
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Academic Article
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A Closer Look at EGFR Inhibitor Resistance in Non-Small Cell Lung Cancer through the Lens of Precision Medicine.
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Concept
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Cell Self Renewal
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Concept
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Celecoxib
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Concept
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Bevacizumab
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Concept
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Clinical Studies as Topic
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Concept
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Imatinib Mesylate
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Concept
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Cetuximab
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Concept
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Capecitabine
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Concept
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Machine Learning
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Concept
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Bortezomib
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Concept
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Tensins
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Concept
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Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Concept
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PAX3 Transcription Factor
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Concept
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Ku Autoantigen
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Concept
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Forkhead Box Protein M1
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Concept
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A549 Cells
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Concept
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PAX8 Transcription Factor
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Concept
|
Src Homology 2 Domain-Containing, Transforming Protein 1
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Concept
|
Gene Editing
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Concept
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Maternal Inheritance
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Concept
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PAX6 Transcription Factor
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Concept
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Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases
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Concept
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Protein Domains
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Concept
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Antineoplastic Agents, Immunological
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Concept
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Liquid Biopsy
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Concept
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Cell Surface Display Techniques
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Concept
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MCF-7 Cells
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Concept
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CRISPR-Cas Systems
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Concept
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Endothelin Receptor Antagonists
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Concept
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Cytochrome P-450 CYP2C9
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Concept
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ErbB Receptors
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Grant
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Role of Paxillin in Lung Cancer
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Grant
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MINIMAL RESIDUAL TUMOR IN SMALL CELL LUNG CANCER
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Grant
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Role of c-Met in SCLC and Potential for Novel Therapy
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Grant
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Novel Targeted Therapy in Pancreatic Cancer
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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Academic Article
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Twelve-Month Follow-up of the Immune Response After COVID-19 Vaccination in Patients with Genitourinary Cancers: A Prospective Cohort Analysis.
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Academic Article
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Complete response to chemoimmunotherapy with bevacizumab in synchronous multiple primary cancers: pulmonary adenocarcinoma and sarcomatoid carcinoma.
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Academic Article
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Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer.
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Academic Article
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Recent Advancement in Breast Cancer Research: Insights from Model Organisms-Mouse Models to Zebrafish.
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Academic Article
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Intrinsically disordered proteins and conformational noise: The hypothesis a decade later.
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Academic Article
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LSD1-targeted therapy-a multi-purpose key to unlock immunotherapy in small cell lung cancer.
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Academic Article
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The innate effects of plant secondary metabolites in preclusion of gynecologic cancers: Inflammatory response and therapeutic action.
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Academic Article
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Radiation Sensitivity: The Rise of Predictive Patient-Derived Cancer Models.
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Academic Article
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Clinical Network Systems Biology: Traversing the Cancer Multiverse.
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Academic Article
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Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status.
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Academic Article
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Stereotactic Body Radiation Therapy for Oligoprogressive and Oligorecurrent Non-Small-Cell Lung Cancer.
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Academic Article
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On the Virtues of "Team Medicine"-A City of Hope Perspective.
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Academic Article
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Selpercatinib and Pralsetinib Induced Chylous Ascites in RET-Rearranged Lung Adenocarcinoma: A Case Series.
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Academic Article
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An LC-MS/MS method for simultaneous determination of LB-100 and its active metabolite, endothall, in human plasma.
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Academic Article
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Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors.
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Academic Article
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Chimeric antibody targeting unique epitope on onco-mucin16 reduces tumor burden in pancreatic and lung malignancies.
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Academic Article
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Phase II Trial of Lung Chemoembolization.
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Academic Article
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Targeted Therapies in Early-Stage Resectable Non-Small-Cell Lung Cancer: New Kids on the Block.
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Academic Article
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Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer.
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Academic Article
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Regression of ovarian cancer xenografts by depleting or inhibiting RLIP.
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Academic Article
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A Nexus between Genetic and Non-Genetic Mechanisms Guides KRAS Inhibitor Resistance in Lung Cancer.
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Academic Article
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Artificial intelligence and allied subsets in early detection and preclusion of gynecological cancers.
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Academic Article
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Immune Escape Strategies in Head and Neck Cancer: Evade, Resist, Inhibit, Recruit.
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Academic Article
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Comprehending phenotypic plasticity in cancer and evolution.
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Academic Article
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Intrinsically disordered proteins: Ensembles at the limits of Anfinsen's dogma.
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